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KLHL22

Description kelch like family member 22
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Lysosome
  • Centrosome
  • Polar Microtubule
  • Cytosol
  • Microtubule Cytoskeleton
  • Cul3-RING Ubiquitin Ligase Complex
  • Intracellular Membrane-bounded Organelle
  • Intercellular Bridge
  • Mitotic Spindle
Molecular Function
  • Protein Binding
  • 14-3-3 Protein Binding
Biological Process
  • Mitotic Sister Chromatid Segregation
  • Protein Monoubiquitination
  • Mitotic Spindle Assembly Checkpoint
  • Negative Regulation Of Autophagy
  • Positive Regulation Of Cell Growth
  • Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
  • Post-translational Protein Modification
  • Cell Division
  • Cellular Response To Leucine
  • Positive Regulation Of TORC1 Signaling
Pathways
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
  • Lung function (FEV1/FVC) ( 30061609)
  • Retinopathy in non-diabetics ( 23393555)
Interacting Genes 2 interacting genes: ADRA1A PLK1
Entrez ID 84861
HPRD ID 07858
Ensembl ID ENSG00000099910
Uniprot IDs Q53GT1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025