ALG12

Description		ALG12 alpha-1,6-mannosyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Alpha-1,6-mannosyltransferase Activity Mannosyltransferase Activity Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol Alpha-1,6-mannosyltransferase
	Biological Process	Protein Folding Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Mannosylation
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG12 causes ALG12-CDG (CDG-1g)
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type I
GWAS		Acne (severe) ( 24927181) Platelet count ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		2 interacting genes: PRDX4 RPL13A
Entrez ID		79087
HPRD ID		06189
Ensembl ID		ENSG00000182858
Uniprot IDs		A0A024R4V6 Q9BV10
PDB IDs
Enriched GO Terms of Interacting Partners?
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