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XRCC2

Description X-ray repair cross complementing 2
Image No pdb structure
GO Annotations Cellular Component
  • Nucleoplasm
  • Replication Fork
  • Cytoplasm
  • Centrosome
  • Rad51B-Rad51C-Rad51D-XRCC2 Complex
  • Intracellular Membrane-bounded Organelle
Molecular Function
  • Four-way Junction DNA Binding
  • Protein Binding
  • ATP Binding
  • DNA-dependent ATPase Activity
Biological Process
  • Mitotic Cell Cycle
  • Double-strand Break Repair Via Homologous Recombination
  • In Utero Embryonic Development
  • Somitogenesis
  • DNA Repair
  • Centrosome Cycle
  • Response To X-ray
  • Response To Gamma Radiation
  • Multicellular Organism Growth
  • Strand Invasion
  • Negative Regulation Of Neuron Apoptotic Process
  • Positive Regulation Of Neurogenesis
  • Meiotic Cell Cycle
  • Regulation Of Fibroblast Apoptotic Process
Pathways
  • HDR through Homologous Recombination (HRR)
  • Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
  • Resolution of D-loop Structures through Holliday Junction Intermediates
  • Homologous DNA Pairing and Strand Exchange
  • Presynaptic phase of homologous DNA pairing and strand exchange
Drugs
Diseases
GWAS
  • Diabetic kidney disease ( 26305897)
  • Mean platelet volume ( 32888494 27863252)
  • Palmitic acid (16:0) levels ( 23362303)
Interacting Genes 5 interacting genes: MEOX2 NKIRAS1 RAD51 RAD51D WFDC1
Entrez ID 7516
HPRD ID 02656
Ensembl ID ENSG00000196584
Uniprot IDs A0A384MEK2 O43543
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025