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C8G

Description complement C8 gamma chain
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Membrane Attack Complex
  • Extracellular Exosome
  • Blood Microparticle
Molecular Function
  • Complement Binding
  • Protein Binding
  • Retinol Binding
  • Protein-containing Complex Binding
Biological Process
  • Complement Activation, Alternative Pathway
  • Complement Activation, Classical Pathway
  • Cytolysis
  • Regulation Of Complement Activation
Pathways
  • Terminal pathway of complement
  • Regulation of Complement cascade
Drugs
  • Zinc
  • Lauric acid
  • Citric acid
  • Zinc acetate
Diseases
  • Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
GWAS
  • Blood protein levels ( 29875488)
Interacting Genes 2 interacting genes: C8A UBQLN2
Entrez ID 733
HPRD ID 00407
Ensembl ID ENSG00000176919
Uniprot IDs P07360
PDB IDs 1IW2 1LF7 2OVA 2OVD 2OVE 2QOS 2RD7 3OJY 6H03 6H04
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025