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HRH4

Description histamine receptor H4
Image No pdb structure
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Dendrite
  • Synapse
Molecular Function
  • Histamine Receptor Activity
  • G Protein-coupled Serotonin Receptor Activity
  • G Protein-coupled Acetylcholine Receptor Activity
  • Neurotransmitter Receptor Activity
Biological Process
  • Inflammatory Response
  • G Protein-coupled Receptor Signaling Pathway
  • G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
  • Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway
  • Positive Regulation Of Cytosolic Calcium Ion Concentration
  • Chemical Synaptic Transmission
  • Biological_process
  • Regulation Of MAPK Cascade
  • G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways
  • Histamine receptors
  • G alpha (i) signalling events
Drugs
  • Amitriptyline
  • Clozapine
  • Loxapine
  • Chlorpromazine
  • Amoxapine
  • Doxepin
  • Aripiprazole
  • Pheniramine
  • REV131
  • Histamine
  • Mianserin
Diseases
GWAS
  • Adult body size ( 32376654)
  • Chronotype ( 30696823)
  • Diastolic blood pressure x educational attainment (graduated college) interaction (2df) ( 32372009)
  • Response to taxane treatment (docetaxel) ( 23006423)
Novel Interacting Genes 2 novel interacting genes: ALMS1 SERPINB7
Interacting Genes 4 interacting genes: CCL16 GNA15 GNAI1 GNAO1
Entrez ID 59340
HPRD ID 06004
Ensembl ID ENSG00000134489
Uniprot IDs B2KJ49 Q9H3N8
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025