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ARRDC3

Description arrestin domain containing 3
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Lysosome
  • Endosome
  • Early Endosome
  • Plasma Membrane
Molecular Function
  • Protein Binding
  • Beta-3 Adrenergic Receptor Binding
Biological Process
  • Temperature Homeostasis
  • Protein Transport
  • Negative Regulation Of Heat Generation
  • Skin Development
  • Positive Regulation Of Ubiquitin-protein Transferase Activity
  • Fat Pad Development
  • Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
  • Negative Regulation Of Locomotion Involved In Locomotory Behavior
  • Negative Regulation Of Cold-induced Thermogenesis
Pathways
Drugs
Diseases
GWAS
  • Breast cancer ( 29059683 25038754)
  • Breast cancer (prognosis) ( 23319801)
  • Breast cancer (survival) ( 25526632)
  • Platelet distribution width ( 32888494)
  • Subcutaneous adipose tissue ( 22589738)
Interacting Genes 40 interacting genes: ADRB2 BAG3 BCL6 CCDC50 CDA DCUN1D1 EFEMP2 EPN2 F2R FAM90A1 HPGDS ITCH MAGI2 MORF4L1 NEDD4L OPTN OTUB2 PDCD6IP PHF1 PRKAA2 RABGEF1 RACK1 RAD18 SMARCD1 STAM2 TNFAIP3 TOLLIP TRIM42 UBA52 UBAC1 UBASH3A UBE2D1 UBE2D2 UBE2E2 UBE2E3 UBQLN2 WWOX WWP1 WWP2 ZRANB1
Entrez ID 57561
HPRD ID 09810
Ensembl ID ENSG00000113369
Uniprot IDs Q96B67
PDB IDs 4N7H 4R7V 4R7X
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025