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AICDA

Description activation induced cytidine deaminase
Image
GO Annotations Cellular Component
  • P-body
  • Nucleus
  • Cytoplasm
  • Protein-containing Complex
Molecular Function
  • RNA Binding
  • Cytidine Deaminase Activity
  • Protein Binding
  • Zinc Ion Binding
  • Ubiquitin Protein Ligase Binding
  • Identical Protein Binding
  • Deoxycytidine Deaminase Activity
Biological Process
  • MRNA Processing
  • Cytidine Deamination
  • Negative Regulation Of Transposition
  • Somatic Diversification Of Immunoglobulins
  • Somatic Hypermutation Of Immunoglobulin Genes
  • Cytidine To Uridine Editing
  • B Cell Differentiation
  • Regulation Of Nuclear Cell Cycle DNA Replication
  • Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
  • Defense Response To Virus
  • DNA Cytosine Deamination
  • DNA Demethylation
  • Negative Regulation Of DNA Methylation-dependent Heterochromatin Assembly
Pathways
Drugs
Diseases
  • Hyper IgM syndromes, autosomal recessive type, including the following three diseases: Activation-induced cytidine deaminase (AICD) defect; Uracil nucleotide glycoside glycosylase (UNG) defect; Immunodeficiency with hyper-IgM type 3
GWAS
  • Takayasu arteritis ( 25604533)
Interacting Genes 6 interacting genes: APP NEDD4L PRKDC PSME3 RNF126 RPA1
Entrez ID 57379
HPRD ID 05585
Ensembl ID ENSG00000111732
Uniprot IDs Q546Y9 Q6QJ80 Q7Z599 Q9GZX7
PDB IDs 5JJ4 5W0R 5W0U 5W0Z 5W1C
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025