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CDCA8

Description cell division cycle associated 8
Image
GO Annotations Cellular Component
  • Chromosome, Centromeric Region
  • Nucleoplasm
  • Nucleolus
  • Cytosol
  • Chromocenter
  • Midbody
  • Chromosome Passenger Complex
  • Protein-containing Complex
  • Intercellular Bridge
  • Spindle Midzone
Molecular Function
  • Protein Binding
Biological Process
  • Mitotic Sister Chromatid Segregation
  • Mitotic Metaphase Plate Congression
  • Chromosome Organization
  • Cell Division
Pathways
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • SUMOylation of DNA replication proteins
  • RHO GTPases Activate Formins
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
  • Axial length ( 24144296)
  • Eyebrow thickness ( 26926045)
Interacting Genes 26 interacting genes: AURKB BIRC5 EMILIN1 FBXO17 GYS1 H3C14 HLA-DRB3 HMBOX1 INCENP MAPKAPK5 NEK3 NKAPD1 NTAQ1 PIAS2 PIH1D2 RANBP2 RPRD1B SENP3 SET SGO1 SGO2 SNAPC5 SPANXN2 TTK UBE2I ZNF277
Entrez ID 55143
HPRD ID 13017
Ensembl ID ENSG00000134690
Uniprot IDs Q53HL2
PDB IDs 2KDD 2QFA 2RAW 2RAX 6YIE 6YIF 6YIH
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025