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PCK2

Description phosphoenolpyruvate carboxykinase 2, mitochondrial
Image No pdb structure
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Matrix
  • Cytosol
Molecular Function
  • Phosphoenolpyruvate Carboxykinase Activity
  • Phosphoenolpyruvate Carboxykinase (GTP) Activity
  • Protein Binding
  • GTP Binding
  • Manganese Ion Binding
Biological Process
  • Gluconeogenesis
  • Oxaloacetate Metabolic Process
  • NADH Oxidation
  • Propionate Catabolic Process
  • Positive Regulation Of Insulin Secretion
  • Response To Lipopolysaccharide
  • Cellular Response To Insulin Stimulus
  • Response To Lipid
  • Response To Starvation
  • Glycerol Biosynthetic Process From Pyruvate
  • Hepatocyte Differentiation
  • Cellular Response To Glucose Stimulus
  • Cellular Response To Tumor Necrosis Factor
  • Cellular Response To Dexamethasone Stimulus
Pathways
  • Gluconeogenesis
Drugs
Diseases
GWAS
  • Liver fibrosis and steatohepatitis severity (MRI cT1 measure) ( 32247823)
Interacting Genes 3 interacting genes: APP EP300 SMAD3
Entrez ID 5106
HPRD ID 02026
Ensembl ID ENSG00000100889
Uniprot IDs A0A384MTT2 Q16822
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025