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NAIP

Description NLR family apoptosis inhibitory protein
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Basolateral Plasma Membrane
  • IPAF Inflammasome Complex
Molecular Function
  • Protein Binding
  • ATP Binding
  • Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
  • Metal Ion Binding
Biological Process
  • Apoptotic Process
  • Inflammatory Response
  • Nervous System Development
  • Detection Of Bacterium
  • Defense Response To Bacterium
  • Negative Regulation Of Apoptotic Process
  • Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
  • Negative Regulation Of Neuron Apoptotic Process
  • Innate Immune Response
  • Pyroptosis
Pathways
Drugs
Diseases
  • Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
GWAS
Interacting Genes 3 interacting genes: CASP9 HPCA MAP3K7
Entrez ID 4671
HPRD ID 09049
Ensembl ID ENSG00000249437
Uniprot IDs Q13075
PDB IDs 2VM5
Enriched GO Terms of Interacting Partners?
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