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EPCAM

Description epithelial cell adhesion molecule
Image
GO Annotations Cellular Component
  • Plasma Membrane
  • Bicellular Tight Junction
  • Integral Component Of Membrane
  • Basolateral Plasma Membrane
  • Apical Plasma Membrane
  • Lateral Plasma Membrane
  • Extracellular Exosome
Molecular Function
  • Protein Binding
  • Protein-containing Complex Binding
  • Cadherin Binding Involved In Cell-cell Adhesion
Biological Process
  • Positive Regulation Of Cell Population Proliferation
  • Signal Transduction Involved In Regulation Of Gene Expression
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Stem Cell Differentiation
  • Leukocyte Migration
  • Cell-cell Adhesion
  • Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin
  • Positive Regulation Of Stem Cell Proliferation
Pathways
  • Cell surface interactions at the vascular wall
Drugs
  • Oportuzumab monatox
  • ING-1
  • Catumaxomab
  • Technetium Tc-99m nofetumomab merpentan
  • Hypromellose
Diseases
  • Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome
GWAS
  • epithelial cell adhesion molecule levels ( 25147954)
Interacting Genes 2 interacting genes: CLDN7 TSC22D2
Entrez ID 4072
HPRD ID 01709
Ensembl ID ENSG00000119888
Uniprot IDs P16422
PDB IDs 4MZV 6I07
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025