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FFAR1

Description free fatty acid receptor 1
Image
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
Molecular Function
  • G Protein-coupled Receptor Activity
  • Lipid Binding
  • Bioactive Lipid Receptor Activity
Biological Process
  • G Protein-coupled Receptor Signaling Pathway
  • Positive Regulation Of Cytosolic Calcium Ion Concentration
  • Insulin Secretion
  • Positive Regulation Of Insulin Secretion
  • Negative Regulation Of Interleukin-1 Beta Production
  • Glucose Homeostasis
  • Positive Regulation Of Calcium Ion Transport
  • Response To Fatty Acid
Pathways
  • Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
  • Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
  • G alpha (q) signalling events
  • Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
  • Free fatty acid receptors
Drugs
  • Icosapent
Diseases
GWAS
Interacting Genes 2 interacting genes: GNAI1 GNAQ
Entrez ID 2864
HPRD ID 04822
Ensembl ID ENSG00000126266
Uniprot IDs O14842
PDB IDs 4PHU 5KW2 5TZR 5TZY
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025