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P4HA3

Description prolyl 4-hydroxylase subunit alpha 3
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Lumen
Molecular Function
  • Procollagen-proline 4-dioxygenase Activity
  • Iron Ion Binding
  • Protein Binding
  • Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen
  • L-ascorbic Acid Binding
Biological Process
  • Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Pathways
  • Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS
  • Hippocampal atrophy ( 25625606)
Interacting Genes 50 interacting genes: ACOT8 ADRA2C ANAPC11 ATN1 B9D2 BAG4 BLOC1S2 C1orf112 C1QTNF2 CERCAM CKMT2 CLPP CT55 CTAG1A CTAG1B CTNNBIP1 DTNBP1 FAM136A GGA3 GPSM3 HGS KRTAP19-5 KRTAP6-1 KRTAP8-1 LRP2BP MAGEA2 MAGEA2B MAGEC2 MCCD1 MEOX2 MSRA NDN NICN1 NUTM1 OIP5 P4HB PROP1 PSMB4 RBFOX1 RUSC1 SCARA5 SERTAD1 SERTAD3 STMN3 TLE5 TOX2 VPS37C WDR62 ZBTB7B ZC3H12A
Entrez ID 283208
HPRD ID 16413
Ensembl ID ENSG00000149380
Uniprot IDs Q7Z4N8
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025