Wiki-Pi

  • About
  • Search
  • Browse
  • People
  • Updates

INPP5J

Description inositol polyphosphate-5-phosphatase J
Image No pdb structure
GO Annotations Cellular Component
  • Ruffle
  • Cytoplasm
  • Cytosol
  • Plasma Membrane
  • Extrinsic Component Of Membrane
  • Growth Cone
  • Dendritic Shaft
Molecular Function
  • Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity
  • Inositol-polyphosphate 5-phosphatase Activity
  • Protein Binding
  • SH3 Domain Binding
  • Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
  • Inositol-1,4,5-trisphosphate 5-phosphatase Activity
  • Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
Biological Process
  • Phosphatidylinositol Biosynthetic Process
  • Negative Regulation Of Neuron Projection Development
  • Negative Regulation Of Microtubule Polymerization
  • Negative Regulation Of Peptidyl-serine Phosphorylation
  • Inositol Phosphate Metabolic Process
  • Inositol Phosphate Dephosphorylation
  • Phosphatidylinositol Dephosphorylation
Pathways
  • Synthesis of PIPs at the plasma membrane
  • Synthesis of IP2, IP, and Ins in the cytosol
  • Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS
  • Fish- and plant-related diet ( 32066663)
  • Gut microbiota (beta diversity) ( 27723756)
  • Oily fish consumption ( 32066663)
  • Pork consumption ( 32066663)
Interacting Genes 18 interacting genes: CDC23 CEP70 DNAJA3 EFHC2 EPS8 FXR2 GOLGA2 HSF2BP MEOX1 MEOX2 PELI1 PICK1 PRKAR1B PSME3 RINT1 TLE5 TRIM27 TRIM54
Entrez ID 27124
HPRD ID 07573
Ensembl ID ENSG00000185133
Uniprot IDs A0A087WVS7 B4DF95 Q15735
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025