SIRT4

Description		sirtuin 4
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	NAD+ ADP-ribosyltransferase Activity Protein Binding Zinc Ion Binding NAD-dependent Protein Deacetylase Activity Biotinidase Activity Lipoamidase Activity NAD+ Binding
	Biological Process	Regulation Of Glutamine Family Amino Acid Metabolic Process Protein ADP-ribosylation Glutamine Metabolic Process Cellular Response To DNA Damage Stimulus Mitochondrion Organization Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Peptidyl-lysine Deacetylation Negative Regulation Of Fatty Acid Oxidation Negative Regulation Of Insulin Secretion Positive Regulation Of Lipid Biosynthetic Process Cellular Response To Hypoxia Tricarboxylic Acid Metabolic Process Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Regulation Of Pyruvate Dehydrogenase Activity
Pathways		Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)
Interacting Genes		2 interacting genes: PTEN SKP2
Entrez ID		23409
HPRD ID		06837
Ensembl ID		ENSG00000089163
Uniprot IDs		Q9Y6E7
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?