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ARHGEF9

Description Cdc42 guanine nucleotide exchange factor 9
Image
GO Annotations Cellular Component
  • Cytosol
  • Postsynaptic Density
Molecular Function
  • Guanyl-nucleotide Exchange Factor Activity
  • Protein Binding
Biological Process
  • G Protein-coupled Receptor Signaling Pathway
  • Positive Regulation Of Apoptotic Process
  • Regulation Of Catalytic Activity
  • Regulation Of Small GTPase Mediated Signal Transduction
Pathways
  • NRAGE signals death through JNK
  • Rho GTPase cycle
  • G alpha (12/13) signalling events
  • GABA receptor activation
  • GABA receptor activation
Drugs
Diseases
  • Hyperekplexia
  • Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS
  • Male-pattern baldness ( 28196072)
Interacting Genes 11 interacting genes: BCL6 CDC42 FAM90A1 GPHN IHO1 KHDRBS1 PLEKHA5 SMURF1 TBC1D22B TFIP11 TSGA10IP
Entrez ID 23229
HPRD ID 02337
Ensembl ID ENSG00000131089
Uniprot IDs B1AMR3 O43307
PDB IDs 2YSQ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025