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ZFPM1
Description
zinc finger protein, FOG family member 1
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Transcription Repressor Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
RNA Polymerase II Activating Transcription Factor Binding
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
T-helper Cell Lineage Commitment
Outflow Tract Morphogenesis
Atrioventricular Valve Morphogenesis
Mitral Valve Formation
Tricuspid Valve Formation
Heart Development
Blood Coagulation
Regulation Of Definitive Erythrocyte Differentiation
Cell Differentiation
Erythrocyte Differentiation
Megakaryocyte Differentiation
Platelet Formation
Granulocyte Differentiation
Negative Regulation Of Protein Binding
Regulation Of Chemokine Production
Negative Regulation Of Interleukin-4 Production
Positive Regulation Of Interferon-gamma Production
Embryonic Hemopoiesis
Megakaryocyte Development
Negative Regulation Of Fat Cell Differentiation
Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Cardiac Muscle Tissue Morphogenesis
Definitive Erythrocyte Differentiation
Primitive Erythrocyte Differentiation
Negative Regulation Of Mast Cell Differentiation
Ventricular Septum Morphogenesis
Atrial Septum Morphogenesis
Transcriptional Activation By Promoter-enhancer Looping
Pathways
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Basophil count (
32888494
)
Basophil percentage of granulocytes (
27863252
)
Basophil percentage of white cells (
32888494
27863252
)
Bone mineral accretion in asthma (oral corticosteroid dose interaction) (
26025128
)
Calcium levels (
29403010
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Eosinophil counts (
32888494
27863252
)
Eosinophil percentage of granulocytes (
27863252
)
Eosinophil percentage of white cells (
32888494
27863252
)
Hair color (
26926045
)
Hematocrit (
32888494
27863252
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
LDL cholesterol (
30275531
)
LDL cholesterol levels (
32203549
)
Low density lipoprotein cholesterol levels (
29083408
32154731
)
Lymphocyte counts (
32888494
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular hemoglobin concentration (
32888494
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Monocyte count (
32888494
)
Neutrophil percentage of granulocytes (
27863252
)
Platelet count (
29403010
32888494
27863252
)
Platelet distribution width (
32888494
)
Plateletcrit (
32888494
27863252
)
PR interval (
32439900
)
Red blood cell count (
32888494
27863252
)
Red cell distribution width (
32888494
)
Reticulocyte count (
32888494
27863252
)
Reticulocyte fraction of red cells (
32888494
27863252
)
Sum eosinophil basophil counts (
27863252
)
Testicular germ cell tumor (
28604728
28604732
26503584
)
Vascular endothelial growth factor levels (
26910538
)
White blood cell count (basophil) (
29403010
27863252
)
Interacting Genes
6 interacting genes:
CTBP2
GATA1
GATA2
GIPC1
GSK3B
TOP3B
Entrez ID
161882
HPRD ID
11800
Ensembl ID
ENSG00000179588
Uniprot IDs
Q8IX07
PDB IDs
2XU7
Enriched GO Terms of Interacting Partners
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