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NOTUM

Description notum, palmitoleoyl-protein carboxylesterase
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Endoplasmic Reticulum Lumen
Molecular Function
  • Phospholipase C Activity
  • Protein Binding
  • Palmitoleyl Hydrolase Activity
Biological Process
  • Wnt Signaling Pathway
  • Negative Regulation Of Wnt Signaling Pathway
  • Post-translational Protein Modification
  • Cellular Protein Metabolic Process
  • Negative Regulation Of Canonical Wnt Signaling Pathway
  • Protein Depalmitoleylation
Pathways
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Release of Hh-Np from the secreting cell
  • Post-translational protein phosphorylation
Drugs
Diseases
GWAS
  • Blond vs. brown/black hair color ( 30531825)
  • Blood protein levels ( 30072576)
  • Diverticular disease ( 30177863)
Interacting Genes 1 interacting genes: ZNF655
Entrez ID 147111
HPRD ID 14073
Ensembl ID ENSG00000185269
Uniprot IDs Q6P988
PDB IDs 4UYU 4UYW 4UYZ 4UZ1 4UZ5 4UZ6 4UZ7 4UZ9 4UZA 4UZL 4UZQ 4WBH 6R8P 6R8Q 6R8R 6T2H 6T2K 6TR5 6TR6 6TR7 6TUZ 6TV4 6YSK 6YUW 6YUY 6YV0 6YV2 6YV4 6YXI
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025