NOTUM

Description		notum, palmitoleoyl-protein carboxylesterase
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GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Lumen
	Molecular Function	Phospholipase C Activity Protein Binding Palmitoleyl Hydrolase Activity
	Biological Process	Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Post-translational Protein Modification Cellular Protein Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Protein Depalmitoleylation
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Release of Hh-Np from the secreting cell Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576) Diverticular disease ( 30177863)
Interacting Genes		1 interacting genes: ZNF655
Entrez ID		147111
HPRD ID		14073
Ensembl ID		ENSG00000185269
Uniprot IDs		Q6P988
PDB IDs		4UYU 4UYW 4UYZ 4UZ1 4UZ5 4UZ6 4UZ7 4UZ9 4UZA 4UZL 4UZQ 4WBH 6R8P 6R8Q 6R8R 6T2H 6T2K 6TR5 6TR6 6TR7 6TUZ 6TV4 6YSK 6YUW 6YUY 6YV0 6YV2 6YV4 6YXI
Enriched GO Terms of Interacting Partners?
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