Virus - Wiki-CORONA

Symbols	Name 1	Name 2	Pathways 1 Hide	Pathways 2 Hide	Drugs 2 Hide	Diseases 2 Hide
AP1G1 and AFTPH	adaptor related protein complex 1 subunit gamma 1	aftiphilin	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
AP1G1 and MAP1A	adaptor related protein complex 1 subunit gamma 1	microtubule associated protein 1A	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis		Estramustine
AP1G1 and ARFRP1	adaptor related protein complex 1 subunit gamma 1	ADP ribosylation factor related protein 1	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Retrograde transport at the Trans-Golgi-Network Retrograde transport at the Trans-Golgi-Network
AP1G1 and RABEP1	adaptor related protein complex 1 subunit gamma 1	rabaptin, RAB GTPase binding effector protein 1	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	TBC/RABGAPs
AP1G1 and SPTB	adaptor related protein complex 1 subunit gamma 1	spectrin beta, erythrocytic	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport		Hereditary elliptocytosis (HE) Hereditary spherocytosis (SPH)
AP1G1 and CLTC	adaptor related protein complex 1 subunit gamma 1	clathrin heavy chain	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Entry of Influenza Virion into Host Cell via Endocytosis Retrograde neurotrophin signalling Retrograde neurotrophin signalling Gap junction degradation Formation of annular gap junctions MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Lysosome Vesicle Biogenesis Recycling pathway of L1 Recycling pathway of L1 WNT5A-dependent internalization of FZD4 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis VLDLR internalisation and degradation LDL clearance
AP1G1 and PSEN2	adaptor related protein complex 1 subunit gamma 1	presenilin 2	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Nuclear signaling by ERBB4 Regulated proteolysis of p75NTR NRIF signals cell death from the nucleus Activated NOTCH1 Transmits Signal to the Nucleus Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus EPH-ephrin mediated repulsion of cells NOTCH3 Activation and Transmission of Signal to the Nucleus NOTCH4 Activation and Transmission of Signal to the Nucleus Noncanonical activation of NOTCH3		Alzheimer's disease (AD)
AP1G1 and SYP	adaptor related protein complex 1 subunit gamma 1	synaptophysin	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
AP1G1 and RABGEF1	adaptor related protein complex 1 subunit gamma 1	RAB guanine nucleotide exchange factor 1	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs
AP1G1 and CLINT1	adaptor related protein complex 1 subunit gamma 1	clathrin interactor 1	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Golgi Associated Vesicle Biogenesis
AP1G1 and UPF1	adaptor related protein complex 1 subunit gamma 1	UPF1 RNA helicase and ATPase	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
AP1G1 and KIF13A	adaptor related protein complex 1 subunit gamma 1	kinesin family member 13A	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Association of TriC/CCT with target proteins during biosynthesis
AP1G1 and BAALC	adaptor related protein complex 1 subunit gamma 1	BAALC binder of MAP3K1 and KLF4	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
AP1G1 and DNER	adaptor related protein complex 1 subunit gamma 1	delta/notch like EGF repeat containing	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Activated NOTCH1 Transmits Signal to the Nucleus
TLE5 and AEN	TLE family member 5, transcriptional modulator	apoptosis enhancing nuclease	Repression of WNT target genes
TLE5 and CARD9	TLE family member 5, transcriptional modulator	caspase recruitment domain family member 9	Repression of WNT target genes	NOD1/2 Signaling Pathway CLEC7A (Dectin-1) signaling		Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
TLE5 and VPS37C	TLE family member 5, transcriptional modulator	VPS37C subunit of ESCRT-I	Repression of WNT target genes	Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
TLE5 and GLRX3	TLE family member 5, transcriptional modulator	glutaredoxin 3	Repression of WNT target genes	Iron uptake and transport
TLE5 and RELA	TLE family member 5, transcriptional modulator	RELA proto-oncogene, NF-kB subunit	Repression of WNT target genes	Activation of NF-kappaB in B cells RIP-mediated NFkB activation via ZBP1 Regulated proteolysis of p75NTR Downstream TCR signaling NF-kB is activated and signals survival Senescence-Associated Secretory Phenotype (SASP) FCERI mediated NF-kB activation DEx/H-box helicases activate type I IFN and inflammatory cytokines production PKMTs methylate histone lysines Transcriptional regulation of white adipocyte differentiation TAK1 activates NFkB by phosphorylation and activation of IKKs complex Interleukin-1 processing SUMOylation of immune response proteins IkBA variant leads to EDA-ID Dectin-1 mediated noncanonical NF-kB signaling CLEC7A (Dectin-1) signaling CD209 (DC-SIGN) signaling CLEC7A/inflammasome pathway The NLRP3 inflammasome Transcriptional Regulation by VENTX Interleukin-1 signaling TRAF6 mediated NF-kB activation Purinergic signaling in leishmaniasis infection	Dimethyl fumarate
TLE5 and VPS37B	TLE family member 5, transcriptional modulator	VPS37B subunit of ESCRT-I	Repression of WNT target genes	Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy

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