SLK

Description		STE20 like kinase
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GO Annotations	Cellular Component	Cytoplasm Cell Leading Edge Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Apoptotic Process Regulation Of Mitotic Cell Cycle Signal Transduction By Protein Phosphorylation Regulation Of Cell Migration Stress-activated Protein Kinase Signaling Cascade Cytoplasmic Microtubule Organization Activation Of Protein Kinase Activity Regulation Of Apoptotic Process Protein Autophosphorylation Regulation Of Focal Adhesion Assembly
Pathways
Drugs		5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE [4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE
Diseases
GWAS		Diastolic blood pressure ( 29403010) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Pulse pressure ( 30487518) Systolic blood pressure ( 30487518) Uterine fibroids ( 21460842 31649266)
Interacting Genes		3 interacting genes: CASP3 CLSTN1 PDZK1
Entrez ID		9748
HPRD ID		11585
Ensembl ID		ENSG00000065613
Uniprot IDs		Q9H2G2
PDB IDs		2J51 2JFL 2JFM 2UV2 4USF 6HVD
Enriched GO Terms of Interacting Partners?
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