CD22

Description		CD22 molecule
Image
GO Annotations	Cellular Component	Cytoplasm Early Endosome Plasma Membrane Cell Surface Integral Component Of Membrane Neuronal Cell Body Membrane Recycling Endosome Extracellular Exosome
	Molecular Function	IgM Binding Signaling Receptor Binding Protein Binding Protein Phosphatase Binding Carbohydrate Binding Sialic Acid Binding CD4 Receptor Binding
	Biological Process	Cell Adhesion Regulation Of Endocytosis Regulation Of B Cell Proliferation B Cell Activation Regulation Of Immune Response Negative Regulation Of Calcium-mediated Signaling Negative Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Immunoglobulin Secretion
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs		Epratuzumab Inotuzumab ozogamicin
Diseases
GWAS
Interacting Genes		17 interacting genes: AP2M1 ATP2B4 CD19 GRB2 HP IGHM INPP5D LCP2 LYN MTDH PIK3R1 PLCG1 PTPN6 PTPRC SHC1 ST6GAL1 SYK
Entrez ID		933
HPRD ID		00114
Ensembl ID		ENSG00000012124
Uniprot IDs		P20273 Q0EAF5
PDB IDs		5VKJ 5VKM 5VL3
Enriched GO Terms of Interacting Partners?
Tagcloud ?