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KHSRP

Description KH-type splicing regulatory protein
Image
GO Annotations Cellular Component
  • Exosome (RNase Complex)
  • Nucleoplasm
  • Cytosol
  • Cytoplasmic Stress Granule
  • Membrane
Molecular Function
  • DNA Binding
  • RNA Binding
  • Protein Binding
  • MRNA 3'-UTR AU-rich Region Binding
Biological Process
  • RNA Splicing, Via Transesterification Reactions
  • Regulation Of Transcription, DNA-templated
  • MRNA Processing
  • MRNA Catabolic Process
  • RNA Splicing
  • MiRNA Metabolic Process
  • Negative Regulation Of Low-density Lipoprotein Particle Clearance
  • Regulation Of MRNA Stability
  • Negative Regulation Of Nitric Oxide Biosynthetic Process
  • MRNA Transport
  • Positive Regulation Of MRNA Catabolic Process
  • 3'-UTR-mediated MRNA Destabilization
  • Cellular Response To Cytokine Stimulus
  • Regulation Of MiRNA Metabolic Process
Pathways
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • KSRP (KHSRP) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
Drugs
  • Resveratrol
  • Artenimol
Diseases
GWAS
Interacting Genes 15 interacting genes: A1CF APBB1 BACE1 EXOSC2 EXOSC3 GADD45A GCC1 GSK3B HNRNPA1 HNRNPH1 KLHL12 PARN PTBP2 STK3 UBE2I
Entrez ID 8570
HPRD ID 10350
Ensembl ID ENSG00000088247
Uniprot IDs Q92945
PDB IDs 2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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