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LGR5

Description leucine rich repeat containing G protein-coupled receptor 5
Image
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Trans-Golgi Network Membrane
Molecular Function
  • Transmembrane Signaling Receptor Activity
  • G Protein-coupled Receptor Activity
  • Protein Binding
  • G Protein-coupled Peptide Receptor Activity
  • Protein-hormone Receptor Activity
Biological Process
  • Hair Follicle Development
  • G Protein-coupled Receptor Signaling Pathway
  • Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
  • Activation Of Adenylate Cyclase Activity
  • Hormone-mediated Signaling Pathway
  • Oocyte Differentiation
  • Regulation Of Cell Proliferation
  • Inner Ear Development
  • Positive Regulation Of Canonical Wnt Signaling Pathway
  • Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis
Pathways
  • Regulation of FZD by ubiquitination
Drugs
Diseases
GWAS
  • Asthma (adult onset) ( 31036433)
  • Asthma (childhood onset) ( 31036433)
  • Type 2 diabetes ( 22885922 18372903 29358691 30297969 20581827)
Interacting Genes 2 interacting genes: REEP5 RSPO2
Entrez ID 8549
HPRD ID 05979
Ensembl ID ENSG00000139292
Uniprot IDs A0A0A8K8C7 O75473
PDB IDs 4BSR 4BSS 4BST 4BSU 4KNG 4UFR 4UFS
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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