ZIC3

Description		Zic family member 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Heart Looping Regulation Of Transcription By RNA Polymerase II Determination Of Left/right Symmetry Central Nervous System Development Anterior/posterior Pattern Specification Cell Differentiation Lung Development Somatic Stem Cell Population Maintenance Determination Of Pancreatic Left/right Asymmetry Determination Of Left/right Asymmetry In Nervous System Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Determination Of Digestive Tract Left/right Asymmetry Determination Of Liver Left/right Asymmetry
Pathways		POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation of pluripotent stem cells
Drugs
Diseases		Heterotaxy; Situs ambiguus
GWAS
Interacting Genes		6 interacting genes: CTNNB1 GLI3 POFUT1 SRF TP53 TWIST1
Entrez ID		7547
HPRD ID		02225
Ensembl ID		ENSG00000156925
Uniprot IDs		O60481
PDB IDs		2EJ4 2RPC
Enriched GO Terms of Interacting Partners?
Tagcloud ?