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WIPF1

Description WAS/WASL interacting protein family member 1
Image
GO Annotations Cellular Component
  • Ruffle
  • Cytosol
  • Actin Filament
  • Actin Cytoskeleton
  • Actin Cortical Patch
  • Cytoplasmic Vesicle
Molecular Function
  • Actin Binding
  • Protein Binding
  • Profilin Binding
  • SH3 Domain Binding
  • Actin Filament Binding
Biological Process
  • Actin Cortical Patch Assembly
  • Endocytosis
  • Actin Polymerization Or Depolymerization
  • Regulation Of Cell Shape
  • Actin Filament-based Movement
  • Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
  • Positive Regulation Of Actin Nucleation
  • Actin Cortical Patch Localization
  • Response To Other Organism
  • Protein-containing Complex Assembly
Pathways
  • Regulation of actin dynamics for phagocytic cup formation
  • Regulation of actin dynamics for phagocytic cup formation
  • RHO GTPases Activate WASPs and WAVEs
  • RHO GTPases Activate WASPs and WAVEs
  • FCGR3A-mediated phagocytosis
  • FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
  • Atrial fibrillation ( 30061737 29892015)
  • Pulse pressure ( 27841878)
  • Resting heart rate ( 27798624)
  • Systolic blood pressure ( 27841878)
  • Urate levels (BMI interaction) ( 25811787)
Interacting Genes 22 interacting genes: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CDC42 CRKL CTTN FASTK GRB2 HCK HOMER3 ITSN2 NCK1 PRKCQ PRPF40A SEC24C WAS WASL WBP4 WWP2 ZAP70
Entrez ID 7456
HPRD ID 03835
Ensembl ID ENSG00000115935
Uniprot IDs A0A140VJZ9 O43516 Q2YDC4
PDB IDs 2A41
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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