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C7

Description complement C7
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Membrane Attack Complex
  • Cell
  • Extracellular Exosome
Molecular Function
Biological Process
  • Cellular Sodium Ion Homeostasis
  • Complement Activation
  • Complement Activation, Alternative Pathway
  • Complement Activation, Classical Pathway
  • Cytolysis
  • Regulation Of Complement Activation
Pathways
  • Terminal pathway of complement
  • Regulation of Complement cascade
Drugs
Diseases
  • Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
GWAS
  • Blood protein levels ( 30072576 29875488 28240269)
  • Clozapine-induced cytotoxicity ( 25656473)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes 3 interacting genes: C5 CLU PLG
Entrez ID 730
HPRD ID 01957
Ensembl ID ENSG00000112936
Uniprot IDs P10643 Q05CI3
PDB IDs 2WCY 6H03 6H04
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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