D2HGDH

Description		D-2-hydroxyglutarate dehydrogenase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	(R)-2-hydroxyglutarate Dehydrogenase Activity FAD Binding
	Biological Process	2-oxoglutarate Metabolic Process Response To Manganese Ion Response To Zinc Ion Response To Cobalt Ion Response To Magnesium Ion Cellular Protein Metabolic Process Response To Calcium Ion Oxidation-reduction Process
Pathways		Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 31361310) Allergy ( 27182965) Artificially sweetened beverage consumption ( 31046077) Asthma ( 31361310 30929738 27182965 31619474) Asthma (adult onset) ( 31036433 30929738) Asthma (childhood onset) ( 31036433 30929738) Asthma (moderate or severe) ( 30552067) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eczema ( 31361310) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Medication use (adrenergics, inhalants) ( 31015401) Medication use (antihistamines for systemic use) ( 31015401) Medication use (glucocorticoids) ( 31015401) Neutrophil percentage of granulocytes ( 27863252) Serum cancer antigen 125 levels ( 31666285) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		1 interacting genes: STK11
Entrez ID		728294
HPRD ID
Ensembl ID		ENSG00000180902
Uniprot IDs		B3KSR6 B4E3K7 B5MCV2 Q8N465
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?