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TPH1

Description tryptophan hydroxylase 1
Image
GO Annotations Cellular Component
  • Cytosol
  • Neuron Projection
Molecular Function
  • Tryptophan 5-monooxygenase Activity
  • Iron Ion Binding
Biological Process
  • Circadian Rhythm
  • Aromatic Amino Acid Family Metabolic Process
  • Negative Regulation Of Ossification
  • Response To Immobilization Stress
  • Serotonin Biosynthetic Process
  • Positive Regulation Of Fat Cell Differentiation
  • Indolalkylamine Biosynthetic Process
  • Bone Remodeling
  • Oxidation-reduction Process
  • Mammary Gland Alveolus Development
Pathways
  • Serotonin and melatonin biosynthesis
  • NGF-stimulated transcription
Drugs
  • Sapropterin
  • LX1031
  • Telotristat
Diseases
GWAS
  • Glucose homeostasis traits ( 30576415)
  • HDL cholesterol ( 30275531)
Interacting Genes 4 interacting genes: APP PRKACA YWHAH YWHAZ
Entrez ID 7166
HPRD ID 01846
Ensembl ID ENSG00000129167
Uniprot IDs P17752
PDB IDs 1IN9 1MLW 3HF6 3HF8 3HFB 5J6D 5L01 5TPG
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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