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BPI

Description bactericidal permeability increasing protein
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Membrane
  • Azurophil Granule Lumen
  • Specific Granule Lumen
  • Extracellular Exosome
Molecular Function
  • Lipopolysaccharide Binding
Biological Process
  • Antimicrobial Humoral Response
  • Lipopolysaccharide-mediated Signaling Pathway
  • Negative Regulation Of Interleukin-6 Production
  • Negative Regulation Of Interleukin-8 Production
  • Negative Regulation Of Tumor Necrosis Factor Production
  • Negative Regulation Of Macrophage Activation
  • Neutrophil Degranulation
  • Innate Immune Response
  • Defense Response To Gram-negative Bacterium
Pathways
  • Toll Like Receptor 4 (TLR4) Cascade
  • Neutrophil degranulation
  • Antimicrobial peptides
Drugs
  • Di-Stearoyl-3-Sn-Phosphatidylcholine
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488)
  • Carboplatin disposition in epthelial ovarian cancer ( 29367611)
Interacting Genes 1 interacting genes: PRSS2
Entrez ID 671
HPRD ID 00174
Ensembl ID ENSG00000101425
Uniprot IDs P17213
PDB IDs 1BP1 1EWF
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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