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PYCR1

Description pyrroline-5-carboxylate reductase 1
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GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Matrix
Molecular Function
  • Pyrroline-5-carboxylate Reductase Activity
  • Protein Binding
  • Identical Protein Binding
Biological Process
  • Proline Biosynthetic Process
  • Cellular Amino Acid Biosynthetic Process
  • Cellular Response To Oxidative Stress
  • Regulation Of Mitochondrial Membrane Potential
  • Oxidation-reduction Process
  • L-proline Biosynthetic Process
  • Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Pathways
  • Glutamate and glutamine metabolism
Drugs
  • NADH
  • L-Proline
Diseases
  • Geroderma osteodysplasticum
GWAS
Interacting Genes 4 interacting genes: BNIPL CDK2AP2 HNRNPD NUDT21
Entrez ID 5831
HPRD ID 01528
Ensembl ID ENSG00000183010
Uniprot IDs A0A024R8U9 E2QRB3 J3QL32 P32322 Q8TBX0
PDB IDs 2GER 2GR9 2GRA 2IZZ 5UAT 5UAU 5UAV 5UAW 5UAX
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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