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PNPLA2

Description patatin like phospholipase domain containing 2
Image No pdb structure
GO Annotations Cellular Component
  • Nucleoplasm
  • Cytoplasm
  • Endoplasmic Reticulum Lumen
  • Endoplasmic Reticulum Membrane
  • Lipid Droplet
  • Cytosol
  • Plasma Membrane
  • Membrane
  • Integral Component Of Membrane
Molecular Function
  • Triglyceride Lipase Activity
Biological Process
  • Negative Regulation Of Sequestering Of Triglyceride
  • Positive Regulation Of Triglyceride Catabolic Process
  • Triglyceride Catabolic Process
  • Lipid Storage
  • Lipid Droplet Organization
  • Acylglycerol Acyl-chain Remodeling
  • Post-translational Protein Modification
  • Cellular Protein Metabolic Process
  • Lipid Homeostasis
Pathways
  • Acyl chain remodeling of DAG and TAG
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Post-translational protein phosphorylation
Drugs
Diseases
GWAS
  • Body fat distribution (arm fat ratio) ( 30664634)
  • Keratoconus ( 31855235)
Interacting Genes 10 interacting genes: ABHD5 ARFGEF2 CYTH2 FAF2 GBF1 MARK3 PHYHIP SERPINF1 SMAD9 UBE2R2
Entrez ID 57104
HPRD ID 11443
Ensembl ID ENSG00000177666
Uniprot IDs Q96AD5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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