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THAP1

Description THAP domain containing 1
Image
GO Annotations Cellular Component
  • Nuclear Chromatin
  • Fibrillar Center
  • Nucleus
  • Nucleoplasm
  • PML Body
  • Intracellular Membrane-bounded Organelle
Molecular Function
  • RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
  • Protein Binding
  • Zinc Ion Binding
  • Identical Protein Binding
  • Protein Homodimerization Activity
  • Sequence-specific DNA Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Endothelial Cell Proliferation
  • Transcription, DNA-templated
  • Regulation Of Transcription, DNA-templated
  • Cell Cycle
  • Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
  • Primary torsion dystonia (PTD)
GWAS
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes 65 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BMS1P1 BYSL C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 EEF1AKNMT FAM124A FAM133A FXR2 GOLGA7 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM10 RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WT1 YES1 ZCCHC10 ZNF385C ZNF408
Entrez ID 55145
HPRD ID 15496
Ensembl ID ENSG00000131931
Uniprot IDs Q9NVV9
PDB IDs 2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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