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CTSA

Description cathepsin A
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Lysosome
  • Endoplasmic Reticulum
  • Membrane
  • Azurophil Granule Lumen
  • Lysosomal Lumen
  • Intracellular Membrane-bounded Organelle
  • Extracellular Exosome
  • Lumenal Side Of Lysosomal Membrane
Molecular Function
  • Carboxypeptidase Activity
  • Serine-type Carboxypeptidase Activity
  • Enzyme Activator Activity
Biological Process
  • Proteolysis
  • Glycosphingolipid Metabolic Process
  • Intracellular Protein Transport
  • Regulation Of Protein Stability
  • Positive Regulation Of Catalytic Activity
  • Neutrophil Degranulation
  • Proteolysis Involved In Cellular Protein Catabolic Process
  • Regulation Of Chaperone-mediated Autophagy
  • Negative Regulation Of Chaperone-mediated Autophagy
Pathways
  • Glycosphingolipid metabolism
  • MHC class II antigen presentation
  • Sialic acid metabolism
  • Defective NEU1 causes sialidosis
  • Neutrophil degranulation
Drugs
Diseases
  • Galactosialidosis
GWAS
Interacting Genes 4 interacting genes: GLB1 LAMP2 LMNA NEU1
Entrez ID 5476
HPRD ID 02020
Ensembl ID ENSG00000064601
Uniprot IDs B4E324 P10619 X6R5C5 X6R8A1
PDB IDs 1IVY 3BP4 3BP7 3BXN 4AZ0 4AZ3 4CI9 4CIA 4CIB 4MWS 4MWT
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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