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PDP1

Description pyruvate dehyrogenase phosphatase catalytic subunit 1
Image No pdb structure
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Matrix
Molecular Function
  • Protein Serine/threonine Phosphatase Activity
  • Magnesium-dependent Protein Serine/threonine Phosphatase Activity
  • [pyruvate Dehydrogenase (lipoamide)] Phosphatase Activity
  • Protein Binding
  • Metal Ion Binding
Biological Process
  • Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate
  • Peptidyl-threonine Dephosphorylation
  • Positive Regulation Of Pyruvate Dehydrogenase Activity
Pathways
  • Regulation of pyruvate dehydrogenase (PDH) complex
Drugs
Diseases
  • Pyruvate dehydrogenase complex deficiency; X-linked Leigh syndrome
GWAS
Interacting Genes 8 interacting genes: ACAT1 CBFA2T2 EGFR FGFR1 PDHA1 PLEKHF2 PRKCD SIRT3
Entrez ID 54704
HPRD ID 16185
Ensembl ID ENSG00000164951
Uniprot IDs A0A024R9C0 Q6P1N1 Q9P0J1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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