TMEM189-UBE2V1

Description		TMEM189-UBE2V1 readthrough
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GO Annotations	Cellular Component
	Molecular Function
	Biological Process
Pathways		NOD1/2 Signaling Pathway TICAM1, RIP1-mediated IKK complex recruitment Downstream TCR signaling FCERI mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 CLEC7A (Dectin-1) signaling Interleukin-1 signaling IRAK1 recruits IKK complex IKK complex recruitment mediated by RIP1 Aggrephagy Aggrephagy TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 27863252)
Interacting Genes		2 interacting genes: TRAF6 UBE2N
Entrez ID		387522
HPRD ID		11926
Ensembl ID		ENSG00000124208
Uniprot IDs		A5PLL7 Q13404
PDB IDs		2A4D 2C2V 2HLW 6D6I
Enriched GO Terms of Interacting Partners?
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