ANXA5

Description		annexin A5
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GO Annotations	Cellular Component	Extracellular Region Intracellular Cytoplasm Cytosol Focal Adhesion External Side Of Plasma Membrane Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Endothelial Microparticle
	Molecular Function	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding
	Biological Process	Platelet Degranulation Signal Transduction Blood Coagulation Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Calcium Ion Transmembrane Transport
Pathways		Platelet degranulation
Drugs		L-Alpha-Glycerophosphorylserine L-thioproline K201 L-Alpha-Glycerophosphorylethanolamine 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid N,O6-Disulfo-Glucosamine 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid Copper
Diseases
GWAS		Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Resting-state electroencephalogram vigilance ( 29703947)
Interacting Genes		17 interacting genes: ACTG1 APP COL10A1 COL2A1 EED EIF4G1 FDFT1 IFNGR2 ITGB5 KDR LAMC3 PPP2R1B SUPT4H1 TERF1 TERF2 TERF2IP TINF2
Entrez ID		308
HPRD ID		00568
Ensembl ID		ENSG00000164111
Uniprot IDs		P08758 V9HWE0
PDB IDs		1ANW 1ANX 1AVH 1AVR 1HAK 1HVD 1HVE 1HVF 1HVG 1SAV 2XO2 2XO3
Enriched GO Terms of Interacting Partners?
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