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RAB18

Description RAB18, member RAS oncogene family
Image
GO Annotations Cellular Component
  • Intracellular
  • Endoplasmic Reticulum Membrane
  • Golgi Apparatus
  • Cytosol
  • Plasma Membrane
  • Endomembrane System
  • Secretory Granule Membrane
  • Synapse
  • Endoplasmic Reticulum Tubular Network
Molecular Function
  • GTPase Activity
  • Protein Binding
  • GTP Binding
  • GDP Binding
Biological Process
  • Eye Development
  • Intracellular Protein Transport
  • Small GTPase Mediated Signal Transduction
  • Brain Development
  • Rab Protein Signal Transduction
  • Lipid Droplet Organization
  • Neutrophil Degranulation
  • Import Into Nucleus
  • Endoplasmic Reticulum Tubular Network Organization
Pathways
  • Neutrophil degranulation
  • COPI-independent Golgi-to-ER retrograde traffic
  • RAB geranylgeranylation
  • RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
  • Warburg micro syndrome
GWAS
  • Childhood ear infection ( 27182965 28928442)
  • Diisocyanate-induced asthma ( 25918132)
  • Heel bone mineral density ( 30598549 28869591)
  • Height ( 31562340)
  • Hip circumference adjusted for BMI ( 28552196)
Interacting Genes 13 interacting genes: APBB1IP CHM DVL3 ERRFI1 FAM107A PDE6D PPP2R1A PPP2R1B PRTFDC1 TAX1BP1 TOM1L1 TREH UCN
Entrez ID 22931
HPRD ID 03731
Ensembl ID ENSG00000099246
Uniprot IDs A0A087X163 B7Z4P9 B7Z5V3 Q9NP72
PDB IDs 1X3S
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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