Wiki-CORONA
  • About
  • Search
  • Browse
  • Data Sources
  • People
  • Funding
  • Advanced Search

KDM1B

Description lysine demethylase 1B
Image
GO Annotations Cellular Component
  • Nucleosome
  • Nuclear Chromatin
  • Nucleus
  • Nucleoplasm
Molecular Function
  • DNA Binding
  • Chromatin Binding
  • Protein Binding
  • Transcription Factor Binding
  • Zinc Ion Binding
  • Oxidoreductase Activity
  • Histone Demethylase Activity (H3-dimethyl-K4 Specific)
  • Histone Demethylase Activity (H3-monomethyl-K4 Specific)
  • Histone Binding
  • Flavin Adenine Dinucleotide Binding
  • FAD Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Regulation Of Gene Expression By Genetic Imprinting
  • Multicellular Organism Development
  • Protein Deubiquitination
  • Histone H3-K4 Demethylation
  • DNA Methylation Involved In Gamete Generation
  • Regulation Of DNA Methylation
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Oxidation-reduction Process
Pathways
  • HDMs demethylate histones
  • UCH proteinases
  • NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS
  • Atrial fibrillation ( 30061737 29892015)
Interacting Genes 2 interacting genes: H3-4 UBE2D3
Entrez ID 221656
HPRD ID 18524
Ensembl ID ENSG00000165097
Uniprot IDs H0Y6H0 Q8NB78
PDB IDs 4FWE 4FWF 4FWJ 4GU0 4GU1 4GUR 4GUS 4GUT 4GUU 4HSU 6R1U 6R25
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

  • Tweet