C9orf72

Description		C9orf72-SMCR8 complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	P-body Extracellular Space Nucleus Cytoplasm Lysosome Endosome Autophagosome Cytoplasmic Stress Granule Dendrite Nuclear Membrane Guanyl-nucleotide Exchange Factor Complex Perikaryon Axonal Growth Cone Main Axon Atg1/ULK1 Kinase Complex
	Molecular Function	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Endocytosis Autophagy Regulation Of Autophagy Positive Regulation Of Macroautophagy Stress Granule Assembly Axon Extension Regulation Of Actin Filament Organization Late Endosome To Lysosome Transport Regulation Of TORC1 Signaling Negative Regulation Of GTP Binding Regulation Of Autophagosome Assembly
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 30976013 25442119 29566793 22959728 27455348 19734901 20801718 24931836) Amyotrophic lateral sclerosis (sporadic) ( 28931804) Delirium ( 29631748) Metabolite levels ( 23823483) PCA3 expression level ( 23555189)
Interacting Genes		7 interacting genes: APP CRX EIF2B2 NMI REL SMN1 SRPK1
Entrez ID		203228
HPRD ID		12975
Ensembl ID		ENSG00000147894
Uniprot IDs		Q96LT7
PDB IDs
Enriched GO Terms of Interacting Partners?
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