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LIN54

Description lin-54 DREAM MuvB core complex component
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
Molecular Function
  • RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
  • Protein Binding
  • Metal Ion Binding
Biological Process
  • Regulation Of Transcription, DNA-templated
  • Cell Cycle
  • Regulation Of Cell Cycle
Pathways
  • Transcription of E2F targets under negative control by DREAM complex
  • Transcription of E2F targets under negative control by DREAM complex
  • Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
  • G0 and Early G1
  • Polo-like kinase mediated events
  • Cyclin E associated events during G1/S transition
  • G1/S-Specific Transcription
  • Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS
  • Lymphocyte percentage of white cells ( 27863252)
  • Pulse pressure ( 30224653 30578418)
  • Red blood cell count ( 29403010 27863252)
  • Systolic blood pressure ( 30578418)
Interacting Genes 1 interacting genes: RB1
Entrez ID 132660
HPRD ID 13218
Ensembl ID ENSG00000189308
Uniprot IDs Q6MZP7 Q7Z3G2
PDB IDs 5FD3
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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