COL10A1

Description		collagen type X alpha 1 chain
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GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Metal Ion Binding
	Biological Process	Skeletal System Development Extracellular Matrix Organization
Pathways		Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Non-integrin membrane-ECM interactions Collagen chain trimerization
Drugs
Diseases		Metaphyseal dysplasias, including: Metaphyseal dysplasia, Schmid type; Metaphyseal dysplasia, McKusik type; Metaphyseal dysplasia, Jansen type; Shwachman-Bodian-Diamond syndrome (SBDS); Metaphyseal anadysplasia (MAD)
GWAS		Age-related macular degeneration ( 23455636 21665990) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Myopia ( 27182965) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		4 interacting genes: ANXA5 BANP P4HB UBQLN1
Entrez ID		1300
HPRD ID		00357
Ensembl ID		ENSG00000123500
Uniprot IDs		Q03692
PDB IDs		1GR3
Enriched GO Terms of Interacting Partners?
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