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DCTN3

Description dynactin subunit 3
Image No pdb structure
GO Annotations Cellular Component
  • Condensed Chromosome Kinetochore
  • Nucleolus
  • Centrosome
  • Spindle
  • Cytosol
  • Dynactin Complex
  • Microtubule
  • Midbody
  • Cleavage Furrow
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • Structural Molecule Activity
  • Protein Binding
Biological Process
  • G2/M Transition Of Mitotic Cell Cycle
  • Mitotic Cell Cycle
  • ER To Golgi Vesicle-mediated Transport
  • Microtubule-based Process
  • Regulation Of G2/M Transition Of Mitotic Cell Cycle
  • Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
  • Cytoskeleton-dependent Cytokinesis
  • Ciliary Basal Body-plasma Membrane Docking
Pathways
  • MHC class II antigen presentation
  • Regulation of PLK1 Activity at G2/M Transition
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • COPI-mediated anterograde transport
  • COPI-independent Golgi-to-ER retrograde traffic
  • AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes 4 interacting genes: ATXN1 DCTN1 GSK3B PBX2
Entrez ID 11258
HPRD ID 06303
Ensembl ID ENSG00000137100
Uniprot IDs O75935 X6RLR1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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