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SEC61B

Description SEC61 translocon subunit beta
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Sec61 Translocon Complex
  • Endoplasmic Reticulum Membrane
  • Cytosol
  • Membrane
  • Integral Component Of Membrane
  • Endoplasmic Reticulum Sec Complex
Molecular Function
  • RNA Binding
  • ARF Guanyl-nucleotide Exchange Factor Activity
  • Protein Binding
  • Epidermal Growth Factor Binding
Biological Process
  • SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation
  • Ubiquitin-dependent ERAD Pathway
  • Retrograde Protein Transport, ER To Cytosol
  • Posttranslational Protein Targeting To Membrane, Translocation
Pathways
  • ER-Phagosome pathway
  • SRP-dependent cotranslational protein targeting to membrane
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS
  • Callous-unemotional behaviour ( 23874384)
  • Gestational age at birth (maternal effect) ( 28877031)
  • Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes 11 interacting genes: APOB ARL6 ATP13A2 BAG6 GET3 GET4 SEC63 SERP1 SPC25 TRAM1 UBL4A
Entrez ID 10952
HPRD ID 06715
Ensembl ID ENSG00000106803
Uniprot IDs P60468
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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