Madhavi Ganapathiraju

Associate Professor of Biomedical Informatics and Intelligent Systems, University of Pittsburgh

Research Areas

Discovery of Protein Interactions
Translational Bioinformatics	Artificial Intelligence
Collective Intelligence	Impact Prediction

Affiliations

Biomedical Informatics Training Program

Intelligent Systems Program

Integrated Systems Biology Program

Joint CMU-Pitt PhD Program in Computational Biology

News

2024 Sep: Review paper describing our clincal trials of two repurposable drugs for schizophrenia is published in Biological Psychiatry!
2024 May: Mesothelioma interactome paper published in BJC Reports
2024 Mar: Paper published in Network Modeling Analysis in Health informatics and Bioinformatics!
Brandan carried out benchmark evaluation of State-of-the-art PPI algorithms! See his paper!

Funding

BRAINS Award from National Institute of Mental Health, NIH (2011)
Title: Discovery of Mental Health and Inflammation (MHAIN) Interactome
Role: Principal Investigator
Supplement Grant to develop website to disseminate results of the BRAINS grant from National Institute of Mental Health, NIH (2012)
Title: Discovery of Mental Health and Inflammation (MHAIN) Interactome
Role: Principal Investigator
Subaward from National Mesothelioma Virtual Bank grant from National Institute for Occupational Safety and Health (NIOSH) (2017)
Title: Mesothelioma Interactome Prediction, Analysis and Dissemination (informal title to describe the scope of the project)
Role: Faculty Investigator
Stanley Medical Research Institute grant to support clinical trial of repurposable drug based on our computational prediction (2018)
Title: Chromoglycate adjunctive therapy for patients with schizophrenia
Role: Co-Investigator
Mesothelioma Applied Research Foundation grant (2019)
Title: Genetic variants, pathways and drug targets of peritoneal mesothelioma
Role: Co-Principal Investigator
Stanley Medical Research Institute grant to support another clinical trial of repurposable drug based on our computational prediction (2019)
Title: A Randomized Controlled Trial of Acetazolamide for Patients with Treatment Resistant Schizophrenia
Role: Consultant
Supplement grant from National Library of Medicine, NIH, to redesign the curriculum of the doctoral training programi (2010)
Title: Pittsburgh Biomedical Informatics Training Program
Role: Co-investigator

Education

Carnegie Mellon University

Ph.D (Language Technologies Institute, School of Computer Science)

Thesis area: Application of statistical natural language processing techniques towards solving specific problems in biology: feature extraction and modeling for transmembrane helix prediction.

Indian Institute of Science (IISc)

ME (Int), Electrical Communications Engineering (ECE)

Delhi University

B.Sc, Mathematics, Electronics, Physics

Resources

Webserver of protein-protein interactions

Lens for Enrichment and Network Studies of Protein

Schizophrenia interactome with 504 novel protein–protein interactions

Global genetic analysis in mice unveils central role for cilia in congenital heart disease

Transmembrane helix prediction using amino acid properties and latent semantic analysis

Interactome of SARS-CoV-2 / nCoV19 modulated host proteins with computationally predicted PPIs

Contact

Email:	madhavi@pitt.edu
Phone:	412-648-9552
Location:	Department of Biomedical Informatics 5607 Baum Blvd Pittsburgh, PA 15206

Administrative Assistant: Linda Mignogna

Grants Administrator: Jesse Kummer