Schizophrenia - Wiki-Pi

Symbols	Name 1	Name 2	Pathways 1 Hide	Pathways 2 Hide	Drugs 1 Hide
PTPRG and PPFIA2	protein tyrosine phosphatase, receptor type, G	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
PTPRN2 and CKAP5	protein tyrosine phosphatase, receptor type, N polypeptide 2	cytoskeleton associated protein 5		Mitotic Prometaphase Organelle biogenesis and maintenance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
PTPRN2 and SPTBN4	protein tyrosine phosphatase, receptor type, N polypeptide 2	spectrin, beta, non-erythrocytic 4		Interaction between L1 and Ankyrins Axon guidance L1CAM interactions NCAM signaling for neurite out-growth
PTPRN2 and UBQLN4	protein tyrosine phosphatase, receptor type, N polypeptide 2	ubiquilin 4
PTPRS and FEZ1	protein tyrosine phosphatase, receptor type, S	fasciculation and elongation protein zeta 1 (zygin I)	ECM proteoglycans
PTPRS and PPFIA2	protein tyrosine phosphatase, receptor type, S	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	ECM proteoglycans	Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
PVRL1 and PARD3	poliovirus receptor-related 1 (herpesvirus entry mediator C)	par-3 family cell polarity regulator	Nectin/Necl trans heterodimerization Cell junction organization Cell-cell junction organization Adherens junctions interactions	Loss of Function of TGFBR2 in Cancer Cell junction organization TGFBR2 MSI Frameshift Mutants in Cancer TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) SMAD2/3 Phosphorylation Motif Mutants in Cancer Tight junction interactions Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer SMAD2/3 MH2 Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer Loss of Function of TGFBR1 in Cancer Cell-cell junction organization Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer SMAD4 MH2 Domain Mutants in Cancer
QARS and PRRC2A	glutaminyl-tRNA synthetase	proline-rich coiled-coil 2A	Cytosolic tRNA aminoacylation tRNA Aminoacylation Mitochondrial tRNA aminoacylation
RAB5A and RIN2	RAB5A, member RAS oncogene family	Ras and Rab interactor 2	Factors involved in megakaryocyte development and platelet production
RAB5B and RIN2	RAB5B, member RAS oncogene family	Ras and Rab interactor 2
RABIF and TCF4	RAB interacting factor	transcription factor 4		CDO in myogenesis Myogenesis
RAB5C and RIN2	RAB5C, member RAS oncogene family	Ras and Rab interactor 2	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
RAC1 and ARHGAP31	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	Rho GTPase activating protein 31	Signaling by GPCR DCC mediated attractive signaling FCERI mediated MAPK activation Signaling by Wnt Nef and signal transduction Signaling by SCF-KIT DAP12 signaling EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Sema4D induced cell migration and growth-cone collapse DAP12 interactions Host Interactions of HIV factors CD28 co-stimulation The role of Nef in HIV-1 replication and disease pathogenesis Factors involved in megakaryocyte development and platelet production GPCR downstream signaling Signaling by VEGF Fc epsilon receptor (FCERI) signaling Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Platelet activation, signaling and aggregation PCP/CE pathway Adaptive Immune System Axon guidance Costimulation by the CD28 family HIV Infection Translocation of GLUT4 to the plasma membrane L1CAM interactions VEGFA-VEGFR2 Pathway EPHB-mediated forward signaling Inactivation of Cdc42 and Rac Ephrin signaling EPH-ephrin mediated repulsion of cells Activation of Rac VEGFR2 mediated vascular permeability Sema4D mediated inhibition of cell attachment and migration G alpha (12/13) signalling events Sema4D in semaphorin signaling Netrin-1 signaling Innate Immune System Signalling by NGF Signal transduction by L1 Cell death signalling via NRAGE, NRIF and NADE Semaphorin interactions p75 NTR receptor-mediated signalling beta-catenin independent WNT signaling CD28 dependent Vav1 pathway DSCAM interactions NRAGE signals death through JNK GPVI-mediated activation cascade Signaling by Robo receptor	Rho GTPase cycle Signaling by Rho GTPases	Guanosine-5\'-Diphosphate
RAC1 and BAG6	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	BCL2-associated athanogene 6	Signaling by GPCR DCC mediated attractive signaling FCERI mediated MAPK activation Signaling by Wnt Nef and signal transduction Signaling by SCF-KIT DAP12 signaling EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Sema4D induced cell migration and growth-cone collapse DAP12 interactions Host Interactions of HIV factors CD28 co-stimulation The role of Nef in HIV-1 replication and disease pathogenesis Factors involved in megakaryocyte development and platelet production GPCR downstream signaling Signaling by VEGF Fc epsilon receptor (FCERI) signaling Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Platelet activation, signaling and aggregation PCP/CE pathway Adaptive Immune System Axon guidance Costimulation by the CD28 family HIV Infection Translocation of GLUT4 to the plasma membrane L1CAM interactions VEGFA-VEGFR2 Pathway EPHB-mediated forward signaling Inactivation of Cdc42 and Rac Ephrin signaling EPH-ephrin mediated repulsion of cells Activation of Rac VEGFR2 mediated vascular permeability Sema4D mediated inhibition of cell attachment and migration G alpha (12/13) signalling events Sema4D in semaphorin signaling Netrin-1 signaling Innate Immune System Signalling by NGF Signal transduction by L1 Cell death signalling via NRAGE, NRIF and NADE Semaphorin interactions p75 NTR receptor-mediated signalling beta-catenin independent WNT signaling CD28 dependent Vav1 pathway DSCAM interactions NRAGE signals death through JNK GPVI-mediated activation cascade Signaling by Robo receptor		Guanosine-5\'-Diphosphate
RAD21 and DISC1	RAD21 homolog (S. pombe)	disrupted in schizophrenia 1	Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Meiotic synapsis Cohesin Loading onto Chromatin Mitotic Anaphase S Phase M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
RALA and EXOC2	v-ral simian leukemia viral oncogene homolog A (ras related)	exocyst complex component 2	Signalling to ERKs Signalling by NGF Signalling to RAS p38MAPK events Translocation of GLUT4 to the plasma membrane NGF signalling via TRKA from the plasma membrane	Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
RANBP2 and HDAC4	RAN binding protein 2	histone deacetylase 4	Mitotic Prometaphase Separation of Sister Chromatids Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown Mitotic Anaphase SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Resolution of Sister Chromatid Cohesion Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport Mitotic Metaphase and Anaphase	Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant NOTCH1 Intracellular Domain Regulates Transcription Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Constitutive Signaling by NOTCH1 PEST Domain Mutants FBXW7 Mutants and NOTCH1 in Cancer
RAP2A and TNIK	RAP2A, member of RAS oncogene family	TRAF2 and NCK interacting kinase		Oxidative Stress Induced Senescence Cellular Senescence	Guanosine-5\'-Triphosphate Guanosine-5\'-Diphosphate
RAP2A and MAP4K4	RAP2A, member of RAS oncogene family	mitogen-activated protein kinase kinase kinase kinase 4		Oxidative Stress Induced Senescence Cellular Senescence	Guanosine-5\'-Triphosphate Guanosine-5\'-Diphosphate
RARA and HDAC4	retinoic acid receptor, alpha	histone deacetylase 4	Generic Transcription Pathway Signaling by Retinoic Acid Nuclear Receptor transcription pathway Orphan transporters	Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant NOTCH1 Intracellular Domain Regulates Transcription Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Constitutive Signaling by NOTCH1 PEST Domain Mutants FBXW7 Mutants and NOTCH1 in Cancer	Adapalene Acitretin Alitretinoin Tazarotene Etretinate Isotretinoin Tamibarotene

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