CCS

Gene Name		copper chaperone for superoxide dismutase
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Superoxide Dismutase Activity Copper Ion Transmembrane Transporter Activity Copper Ion Binding Protein Binding Zinc Ion Binding Protein Disulfide Oxidoreductase Activity
	Biological Process	Response To Reactive Oxygen Species Superoxide Metabolic Process Intracellular Copper Ion Transport Removal Of Superoxide Radicals Copper Ion Transmembrane Transport Positive Regulation Of Oxidoreductase Activity Oxidation-reduction Process
Pathways		Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-protein Interactions		3 interactors: APBA1 SOD1 YWHAG
Entrez ID		9973
HPRD ID		04841
Ensembl ID		ENSG00000173992
Uniprot IDs		O14618
PDB IDs		1DO5 2CRL 2RSQ
Enriched GO Terms of Interacting Partners?		Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Response To Antipsychotic Drug Positive Regulation Of Apoptotic Signaling Pathway Intracellular Transport Locomotory Behavior Negative Regulation Of Cholesterol Biosynthetic Process Gamma-aminobutyric Acid Secretion Response To Carbon Monoxide Microtubule-based Movement Establishment Of Localization In Cell Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Response To Potassium Ion Positive Regulation Of Oxidative Stress-induced Cell Death Nervous System Development Cellular Localization Positive Regulation Of Superoxide Anion Generation Cellular Response To ATP Relaxation Of Vascular Smooth Muscle Auditory Receptor Cell Stereocilium Organization Response To Potassium Ion Gamma-aminobutyric Acid Transport Cellular Response To Organonitrogen Compound Hydrogen Peroxide Biosynthetic Process Relaxation Of Smooth Muscle Retrograde Axon Cargo Transport Secretion By Cell Auditory Receptor Cell Morphogenesis Regulation Of Superoxide Anion Generation Neurofilament Cytoskeleton Organization Positive Regulation Of Apoptotic Process Negative Regulation Of Smooth Muscle Contraction Behavior Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Secretion Superoxide Anion Generation Auditory Receptor Cell Development Cellular Response To Cadmium Ion Inner Ear Receptor Stereocilium Organization Removal Of Superoxide Radicals Regulation Of Cholesterol Biosynthetic Process Cellular Response To Superoxide Negative Regulation Of Muscle Contraction Relaxation Of Muscle Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Protein Kinase Activity Response To Copper Ion Negative Regulation Of Steroid Biosynthetic Process
Tagcloud ?		angina angiographic atherosclerosis braunwald clauss consecutively coronary correlate count degree fibrinogen hundred hyperfibrinogenemia irregularities leucocyte leucocytosis luminal offer pectoris rest sclerosis sixteen stenosis subgroup tendency thrombogenesis unstable vd vessel