FARP2

Gene Name		FERM, RhoGEF and pleckstrin domain protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Extrinsic Component Of Membrane
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Cytoskeletal Protein Binding Rac Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Cell Adhesion Axon Guidance Neuron Remodeling Rac Protein Signal Transduction Osteoclast Differentiation Actin Cytoskeleton Reorganization Positive Regulation Of Rac GTPase Activity Regulation Of Integrin Activation Semaphorin-plexin Signaling Pathway Podosome Assembly
Pathways		Axon guidance Semaphorin interactions SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 20062064) Prostate cancer ( 23535732)
Protein-protein Interactions		4 interactors: PDZK1 SRC UBE2G2 YWHAG
Entrez ID		9855
HPRD ID		16885
Ensembl ID		ENSG00000006607
Uniprot IDs		O94887
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Transport Regulation Of Establishment Of Protein Localization Positive Regulation Of Transport Regulation Of Protein Localization Membrane Organization Cellular Response To Progesterone Stimulus Regulation Of Cellular Localization Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Cellular Response To Insulin Stimulus Positive Regulation Of Intracellular Transport Positive Regulation Of Integrin Activation Negative Regulation Of Mitochondrial Depolarization Positive Regulation Of Podosome Assembly Response To Insulin Negative Regulation Of Protein Homooligomerization Progesterone Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Regulation Of Podosome Assembly Cellular Response To Peptide Positive Regulation Of Protein Transport Regulation Of Caveolin-mediated Endocytosis Osteoclast Development Negative Regulation Of Protein Oligomerization Positive Regulation Of Organelle Organization Regulation Of Integrin Activation Carnitine Transport Regulation Of Early Endosome To Late Endosome Transport Regulation Of Cellular Component Organization Transcytosis Response To Peptide Hormone Cellular Response To Organonitrogen Compound Signal Complex Assembly Stress Fiber Assembly Response To Peptide Negative Regulation Of Anoikis Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Autophosphorylation Response To Drug Uterus Development Intracellular Estrogen Receptor Signaling Pathway Regulation Of Anoikis Response To Acidic PH Quaternary Ammonium Group Transport Regulation Of Mitochondrial Depolarization Positive Regulation Of DNA Biosynthetic Process Negative Regulation Of Focal Adhesion Assembly Cellular Response To Platelet-derived Growth Factor Stimulus Cellular Response To Hormone Stimulus Positive Regulation Of Apoptotic Process Response To Platelet-derived Growth Factor
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