CDC42BPB

Gene Name		CDC42 binding protein kinase beta (DMPK-like)
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Cell Leading Edge Actomyosin Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Small GTPase Regulator Activity ATP Binding Rho GTPase Binding
	Biological Process	Protein Phosphorylation Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Cell Migration Actomyosin Structure Organization Actin Cytoskeleton Reorganization Intracellular Signal Transduction Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Large B-cell lymphoma ( 21471979)
Protein-protein Interactions		3 interactors: CDC42 MAP2K5 RIPK1
Entrez ID		9578
HPRD ID		08516
Ensembl ID		ENSG00000198752
Uniprot IDs		Q86XZ8 Q9Y5S2
PDB IDs		3QFV 3TKU
Enriched GO Terms of Interacting Partners?		Positive Regulation Of MAPK Cascade Positive Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Regulation Of MAPK Cascade Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Positive Regulation Of JNK Cascade Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Protein Phosphorylation Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Signal Transduction Activation Of MAPK Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of ATP:ADP Antiporter Activity Negative Regulation Of Signaling Regulation Of JNK Cascade Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Regulation Of Stress-activated MAPK Cascade Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production ERK5 Cascade Positive Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Necroptotic Process Positive Regulation Of MAP Kinase Activity Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process MAPK Cascade Positive Regulation Of Catalytic Activity Positive Regulation Of Gene Expression Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Apoptotic Signaling Pathway Actin Filament Branching Amyloid Fibril Formation Submandibular Salivary Gland Formation Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation
Tagcloud ?		associating automated bace1 cation csnk2a1 disturbance disturbances enables gsk3 hallmark hela library linker localization m6pr mannose microtubule notably perturbation precise prkaca prkacg spatially states systematically throughput tracking trafficking visual