MED27

Gene Name		mediator complex subunit 27
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm Mediator Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Stem Cell Maintenance
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-protein Interactions		9 interactors: AFP ARFGAP1 MED19 MED22 MED30 MED8 MED9 RBPJ SOX5
Entrez ID		9442
HPRD ID		05438
Ensembl ID		ENSG00000160563
Uniprot IDs		Q6P2C8
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Timing Of Cell Differentiation Regulation Of Development, Heterochronic RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Epidermal Cell Fate Specification Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Positive Regulation Of Ephrin Receptor Signaling Pathway Arterial Endothelial Cell Fate Commitment Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Metabolic Process Blood Vessel Lumenization Blood Vessel Endothelial Cell Fate Specification Nitrogen Compound Metabolic Process Protein Secretion Endothelial Cell Fate Specification Stem Cell Maintenance Clara Cell Differentiation Positive Regulation Of Mesenchymal Stem Cell Differentiation Interleukin-4 Secretion Positive Regulation Of Transcription Of Notch Receptor Target Regulation Of Cellular Process Hair Follicle Maturation Regulation Of Timing Of Neuron Differentiation Auditory Receptor Cell Fate Commitment Dorsal Aorta Morphogenesis Arterial Endothelial Cell Differentiation Regulation Of Mesenchymal Stem Cell Differentiation Dorsal Aorta Development Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Endocardium Morphogenesis Endothelial Tube Morphogenesis
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