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CD8A
Gene Name
CD8a molecule
Image
Gene Ontology Annotations
Cellular Component
Extracellular Region
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
T Cell Receptor Complex
Molecular Function
Protein Binding
Coreceptor Activity
Protein Kinase Binding
MHC Class I Protein Binding
Protein Homodimerization Activity
Biological Process
T Cell Mediated Immunity
Immune Response
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Antigen Processing And Presentation
T Cell Activation
Cytotoxic T Cell Differentiation
Regulation Of Immune Response
Positive Regulation Of Calcium-mediated Signaling
Defense Response To Virus
Pathways
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions
17 interactors:
B2M
CACYBP
CD3D
CD59
CD8B
CDK1
HLA-A
HLA-B
HLA-C
HLA-E
HLA-G
LAT
LCK
LGALS1
PTPRC
SREK1
SRSF1
Entrez ID
925
HPRD ID
01737
Ensembl ID
ENSG00000153563
Uniprot IDs
P01732
Q6ZVS2
Q8TAW8
PDB IDs
1AKJ
1CD8
1Q69
2HP4
3QZW
Enriched GO Terms of Interacting Partners
?
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent
Positive Regulation Of T Cell Mediated Cytotoxicity
Regulation Of T Cell Mediated Cytotoxicity
Regulation Of Immune Response
Positive Regulation Of Immune System Process
Positive Regulation Of Leukocyte Mediated Cytotoxicity
Regulation Of Immune System Process
Positive Regulation Of T Cell Mediated Immunity
Positive Regulation Of Cell Killing
Regulation Of Leukocyte Mediated Cytotoxicity
Positive Regulation Of Immune Response
Positive Regulation Of Adaptive Immune Response
Immune System Process
Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Regulation Of Adaptive Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Interferon-gamma-mediated Signaling Pathway
Regulation Of T Cell Activation
Innate Immune Response
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Cellular Response To Interferon-gamma
Positive Regulation Of T Cell Activation
Regulation Of Cell-cell Adhesion
Positive Regulation Of Homotypic Cell-cell Adhesion
Regulation Of Lymphocyte Activation
Defense Response
Response To Interferon-gamma
Antigen Processing And Presentation Of Endogenous Antigen
Positive Regulation Of Cell-cell Adhesion
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent
Protection From Natural Killer Cell Mediated Cytotoxicity
Type I Interferon Signaling Pathway
Cellular Response To Type I Interferon
Regulation Of Cell Activation
Response To Type I Interferon
Positive Regulation Of Cell Activation
Antigen Processing And Presentation Of Peptide Antigen
Regulation Of Defense Response To Virus By Virus
Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity
Positive Regulation Of Cell Adhesion
Regulation Of Cell Adhesion
Cell Surface Receptor Signaling Pathway
Lymphocyte Activation
Antigen Processing And Presentation
Cell Activation
Negative Regulation Of Immune Response
Leukocyte Activation
T Cell Aggregation
T Cell Activation
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